Stanford researchers blocked an age-linked enzyme called 15-PGDH and watched worn knee cartilage thicken in old mice, protect against post-injury arthritis, and even stir to life in human tissue from knee-replacement patients. Exciting, but still early.
A new Nature study in cancer-prone mice found that a ketogenic diet boosted small-intestinal tumors while suppressing colon tumors, and the culprit was dietary fat burning in stem cells, not ketones.
In mice, stimulating the vagus nerve right after training strengthened motor learning in the following days, and the effect was linked to rhythmic changes in blood volume in the cerebellum.
A 2024 review in Hypertension explains how immune cells, inflammatory signals and even oxidative by-products can help push blood pressure up and damage organs, and why that opens the door to new treatment ideas.
A small randomized trial shows that paricalcitol, an FDA-approved vitamin D analog, can be added safely to chemotherapy and reprogram the fibroblast-rich shield around pancreatic tumors, building on years of research at the Salk Institute.
NASA's Nancy Grace Roman Space Telescope has passed its fine-guidance tests, and its Coronagraph Instrument has captured its first light, two key steps on the way to imaging distant planets.
Researchers at the University of Colorado Anschutz found that the stem cells driving high-risk myelodysplastic syndromes depend heavily on the molecule NAD — a dependence that could become a precise treatment target.
Two giant Australian stick insect species have just been named, one of them with eggs unlike any stick insect on record. The find shows how much insect biodiversity may still be hiding in plain sight.
Long COVID, ME/CFS, PTSD, rheumatoid arthritis and multiple sclerosis start in very different ways, yet all can end in crushing fatigue. A new genomic analysis suggests they may disrupt the same biological networks.