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Reading Human Milk as a Window into the Mammary Gland

A Science study of 1,543 human milk samples from Canada, Pakistan and Burkina Faso finds shared molecular patterns that tie maternal nutrition, mammary gland function and infant growth together, and points to seven candidate biomarkers.

An Injection That Tells Fat Cells to Self-Destruct: What the Early Data Show (and What They Don’t)

An experimental injection called CBL-514 triggers fat cells to die off on their own. Early human data show less visceral belly fat, but the results come from a small conference abstract, not a peer-reviewed paper.

Can Old Knees Regrow Their Cartilage? Blocking an Aging Enzyme Says Maybe

Stanford researchers blocked an age-linked enzyme called 15-PGDH and watched worn knee cartilage thicken in old mice, protect against post-injury arthritis, and even stir to life in human tissue from knee-replacement patients. Exciting, but still early.

High Blood Pressure Is Not Just a Plumbing Problem: How the Immune System Drives Hypertension

A 2024 review in Hypertension explains how immune cells, inflammatory signals and even oxidative by-products can help push blood pressure up and damage organs, and why that opens the door to new treatment ideas.

One Exhaustion, Five Diseases: Is There a Shared Biology Behind Chronic Fatigue?

Long COVID, ME/CFS, PTSD, rheumatoid arthritis and multiple sclerosis start in very different ways, yet all can end in crushing fatigue. A new genomic analysis suggests they may disrupt the same biological networks.

One CRISPR Infusion, One Year Later: Cholesterol and Triglycerides Stay Down by About Half

A single infusion of the experimental CRISPR-Cas9 therapy CTX310 kept LDL cholesterol down 52.5% and triglycerides down 47.8% a year later in a first-in-human trial, with no serious treatment-related adverse events.

Rare Infections During Pregnancy Are Linked to Autism and Intellectual Disability

A Swedish study of 3.7 million people finds that congenital TORCH infections, though rare, are tied to a markedly higher risk of autism and intellectual disability in the child.

Scientists Find a New Layer of Alzheimer’s Hidden in the Genome

When people talk about the biology of Alzheimer's disease, the conversation almost always centers on two culprits: amyloid-beta plaques and tau tangles. A new study from Carnegie Mellon University, the University of Pittsburgh School of Medicine, and the University of... Continue Reading →

Human Hearts Can Regrow Muscle After a Heart Attack, World-First Study Finds

For decades, the working assumption in cardiology has been simple and grim: once heart muscle dies during a heart attack, it's gone for good. A new study from the University of Sydney, the Baird Institute, and Royal Prince Alfred Hospital... Continue Reading →

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