A single-cell analysis of nearly half a million cells from 62 pancreatic tumors shows how cancer cells keep reshaping their genetic activity over time, helping some clones resist therapy and others spread.
A small randomized trial shows that paricalcitol, an FDA-approved vitamin D analog, can be added safely to chemotherapy and reprogram the fibroblast-rich shield around pancreatic tumors, building on years of research at the Salk Institute.
Biomedical engineers at Duke University have demonstrated the most effective treatment for pancreatic cancer ever recorded in mouse models. While most mouse trials consider simply halting growth a success, the new treatment completely eliminated tumors in 80 percent of mice... Continue Reading →