Free radicals have long been seen as purely harmful, but a new Science study finds that cancer-fighting T cells need them, and that tumors release an antioxidant protein, PRDX1, to switch the immune attack off. Here is what was found in mice and what it could mean for immunotherapy.
A 2024 review in Hypertension explains how immune cells, inflammatory signals and even oxidative by-products can help push blood pressure up and damage organs, and why that opens the door to new treatment ideas.
Personalized cell therapies have transformed cancer treatment for some patients, but they share a common problem: each dose has to be custom-built from that patient's own cells, a process that can take weeks and cost hundreds of thousands of dollars.... Continue Reading →
A first cell atlas of the human thymus gland could lead to new immune therapies to treat cancer and autoimmune diseases. Researchers from the Wellcome Sanger Institute, Newcastle University and Ghent University, Belgium, mapped thymus tissue through the human lifespan... Continue Reading →